Pinopodes as markers of endometrial receptivity in clinical practice
نویسندگان
چکیده
منابع مشابه
Pinopodes: a questionable role in endometrial receptivity.
BACKGROUND A better understanding of endometrial receptivity is crucial to the creation and optimization of tests to assess the window of implantation in a clinical setting. Testing endometrial receptivity via scanning electron microscopy of endometrial samples reveals that pinopodes are a very good marker of endometrial receptivity in the rat. There is still disagreement in the literature as t...
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While in-vitro fertilization (IVF) was initially developed in women with tubal factor infertility, recent clinical studies have suggested that the presence of hydrosalpinges lowers implantation and pregnancy rates. We postulated that these hydrosalpinges cause impaired endometrial receptivity. A total of 103 women with hydrosalpinges were prospectively evaluated, and compared with 55 infertile ...
متن کاملEndometrial pinopodes indicate a shift in the window of receptivity in IVF cycles.
The formation of endometrial pinopodes detected by scanning electron microscopy may be a specific marker for uterine receptivity. Aiming to assess the effects of ovarian stimulation on pinopode formation, we examined sequential endometrial biopsies from 17 oocyte donors. Seven normally menstruating women served as controls. Up to four samples were taken from each woman at 24-72 h intervals betw...
متن کاملEndometrial markers of uterine receptivity utilizing the donor oocyte model.
BACKGROUND Ethical constraints limit the ability to study peri-implantation phase human endometrium. In this study, the donor oocyte model was used to study candidate endometrial markers of uterine receptivity. METHODS Archived, paraffin-embedded tissue obtained by endometrial biopsy during cycle days 21-23 of patients undergoing 'mock' hormonal treatment cycles were evaluated by standard his...
متن کاملSubcellular localization of L-selectin ligand in the endometrium implies a novel function for pinopodes in endometrial receptivity
BACKGROUND Apical surfaces of human endometrial epithelium and endothelium are key elements for the initiation of molecular interactions to capture the blastocyst or leukocyte, respectively. The L-selectin adhesion system has been strongly proposed to play an important role in the initial steps of trophoblast adhesion and promotion of integrin-dependent processes, ultimately culminating in the ...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 1999
ISSN: 0268-1161,1460-2350
DOI: 10.1093/humrep/14.suppl_2.99